Clinical Features and Outcomes of Repeated Endoscopic Therapy for Esophagogastric Variceal Hemorrhage in Cirrhotic Patients: Ten-Year Real-World Analysis
Table 2
Factors associated with 5-year mortality.
Variable
Univariate analysis HR (95% CI)
Multivariate analysis HR (95% CI)
Age (year)
1.045 (1.034-1.056)
<0.001
1.048 (1.036-1.059)
<0.001
Sex
1.334 (1.043-1.706)
0.022
WBC (×109/L)
1.044 (1.013-1.077)
0.005
NEU%
1.022 (1.012-1.032)
<0.001
LYM%
0.968 (0.956-0.980)
<0.001
0.986 (0.973-0.999)
0.032
HGB (g/L)
0.989 (0.984-0.993)
<0.001
0.992 (0.987-0.997)
0.002
PLT (×109/L)
1.001 (0.999-1.004)
0.269
ALT (U/L)
1.001 (0.999-1.002)
0.383
AST (U/L)
1.000 (1.000-1.001)
0.260
GGT (U/L)
1.001 (1.000-1.002)
0.027
1.002 (1.001-1.003)
<0.001
TBIL (μmol/L)
1.005 (1.003-1.006)
<0.001
DBIL (μmol/L)
1.006 (1.004-1.009)
<0.001
1.003 (1.000-1.006)
0.025
ALB (g/L)
0.931 (0.914-0.950)
<0.001
0.964 (0.943-0.987)
0.002
Cr (μmol/L)
1.003 (1.002-1.004)
<0.001
INR
3.049 (2.100-4.428)
<0.001
MELD score
1.073 (1.050-1.096)
<0.001
1.057 (1.032-1.083)
<0.001
Child-Pugh score
1.214 (1.150-1.281)
<0.001
WBC: white blood cell; NEU%: neutrophilic granulocyte percentage; LYM%: lymphocytes percentage; HGB: hemoglobin; PLT: platelet count; ALT: alanine transaminase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; TBIL: total bilirubin; DBIL: direct bilirubin; ALB: albumin; Cr: creatinine; INR: international normalized ratio.