Research Article

Clinical Features and Outcomes of Repeated Endoscopic Therapy for Esophagogastric Variceal Hemorrhage in Cirrhotic Patients: Ten-Year Real-World Analysis

Table 2

Factors associated with 5-year mortality.

VariableUnivariate analysis
HR (95% CI)
Multivariate analysis
HR (95% CI)

Age (year)1.045 (1.034-1.056)<0.0011.048 (1.036-1.059)<0.001
Sex1.334 (1.043-1.706)0.022
WBC (×109/L)1.044 (1.013-1.077)0.005
NEU%1.022 (1.012-1.032)<0.001
LYM%0.968 (0.956-0.980)<0.0010.986 (0.973-0.999)0.032
HGB (g/L)0.989 (0.984-0.993)<0.0010.992 (0.987-0.997)0.002
PLT (×109/L)1.001 (0.999-1.004)0.269
ALT (U/L)1.001 (0.999-1.002)0.383
AST (U/L)1.000 (1.000-1.001)0.260
GGT (U/L)1.001 (1.000-1.002)0.0271.002 (1.001-1.003)<0.001
TBIL (μmol/L)1.005 (1.003-1.006)<0.001
DBIL (μmol/L)1.006 (1.004-1.009)<0.0011.003 (1.000-1.006)0.025
ALB (g/L)0.931 (0.914-0.950)<0.0010.964 (0.943-0.987)0.002
Cr (μmol/L)1.003 (1.002-1.004)<0.001
INR3.049 (2.100-4.428)<0.001
MELD score1.073 (1.050-1.096)<0.0011.057 (1.032-1.083)<0.001
Child-Pugh score1.214 (1.150-1.281)<0.001

WBC: white blood cell; NEU%: neutrophilic granulocyte percentage; LYM%: lymphocytes percentage; HGB: hemoglobin; PLT: platelet count; ALT: alanine transaminase; AST: aspartate aminotransferase; GGT: gamma-glutamyl transpeptidase; TBIL: total bilirubin; DBIL: direct bilirubin; ALB: albumin; Cr: creatinine; INR: international normalized ratio.