miR-21 Overexpression Promotes Esophageal Squamous Cell Carcinoma Invasion and Migration by Repressing Tropomyosin 1

Figure 2

The miR-21 overexpression induces ESCC invasion and migration. (a) miR-21 was detected by RT-PCR after inhibition with miR-21 antisense oligonucleotide in EC109 cells. (b) miR-21 was detected by RT-PCR after the overexpression by miR-21 oligonucleotide mimics in EC1 cells. (c) The transwell assay indicating that inhibition of miR-21 inhibits invasion and migration of EC109 cells. (d) The transwell assay indicating that the overexpression of miR-21 promotes invasion and migration of EC1 cells.

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