Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model

Figure 1

Cell modeling of PNALD in vitro. (a) Rat normal hepatocytes BRL were treated with different concentrations of soybean oil emulsion (SO). The degree of steatosis in BRL cells was determined by Oil Red O staining. Scar bar: 50 μm. (b) BRL cell viability was analyzed by the method of CCK-8 after treated with SO. NG: not given (BRL cells untreated with SO). The data was presented as . (c) BRL cell viability was analyzed by the method of CCK-8 after treatment with SO for 48 h. NG: not given (BRL cells untreated with SO). The data was presented as , , . (d) BRL cell viability was analyzed by the method of CCK-8 after treatment with SO for 72 h. NG: not given (BRL cells untreated with SO). The data was presented as , , .

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