Clinical Characterization of Ulcerative Colitis in Patients with Primary Sclerosing Cholangitis
Table 3
Clinical characteristics of the total PSC patient series.
UC group
Non-UC group
value
Gender, male : female
17 : 18
18 : 24
ns
Age at diagnosis of PSC, yrs
<0.0001
Colonoscopy, yes : no
35 : 0
20 : 22
<0.0001
Site of inflammation:
Intrahepatic bile duct
8
7
ns
Extrahepatic bile duct
2
4
ns
Both
24
31
ns
Child-Pugh classification (A/B/C)
24/10/1
25/15/2
ns
Liver biopsy Ludwig’s stage:
Stage I
2
0
ns
Stage II
17
21
ns
Stage III
3
5
ns
Stage IV
1
1
ns
Unknown
12
15
ns
Treatment:
Ursodeoxycholic acid
31
36
ns
At PSC diagnosis:
PT, %
ns
CRP, mg/dl
ns
Alb, g/dl
ns
Total Bil, mg/dl
ns
AST, U/l
ns
ALT, U/l
ns
ALP, U/l
ns
Cr, mg/dl
ns
Na, mEq/l
ns
PSC follow-up period (days)
3254 (229-11825)
1857 (173-9223)
0.0133
Data are the , median (min-max), or the number of patients. Alb: albumin; ALP: alkaline phosphatase; ALT: alanine aminotransferase; AST: aspartate aminotransferase; Bil: bilirubin; Cr: creatinine; CRP: C-reactive protein; Na: sodium; ns: not significant; PT: prothrombin time.
