The Efficacy of Washed Microbiota Transplantation on Helicobacter pylori Eradication: A Pilot Study
Table 1
Associations of age, gender, indications, and procedures of WMT with H. pylori eradication by WMT.
Variable
H. pylori eradicated
H. pylori persistent
value
Age
0.422
Gender
Male ()
6 (31.58)
13 (68.42)
0.208
Female ()
7 (53.85)
6 (46.15)
Indications
IBS ()
5 (26.32)
14 (73.68)
0.120
NAFLD ()
2 (100.00)
0 (0.00)
HE ()
1 (50.00)
1 (50.00)
GERD ()
2 (100.00)
0 (0.00)
GA ()
0 (0.00)
2 (100.00)
AH ()
2 (100.00)
0 (0.00)
HC ()
1 (100.00)
0 (0.00)
FD ()
0 (0.00)
1 (100.00)
ADHD ()
0 (0.00)
1 (100.00)
Delivery route
Middle gastrointestinal tract only ()
7 (58.33)
5 (41.67)
0.152
Lower gastrointestinal tract only ()
1 (16.67)
5 (83.33)
Upper gastrointestinal tract and middle gastrointestinal tract ()
2 (50.00)
2 (50.00)
Middle and lower gastrointestinal tract ()
3 (37.50)
5 (62.50)
Upper, middle and lower gastrointestinal tract ()
0 (0.00)
2 (100.00)
WMT procedures
Course times
0.607
Frequency
0.471
Duration (day)
0.202
Intestinal barrier function ()
Diamine oxidase (U/L)
0.545
D-lactate (U/L)
0.768
Lipopolysaccharide (U/L)
0.332
Gastric function ()
PG I (μg/L)
0.669
PG II (μg/L)
0.114
PG ratio (PG I/PG II)
0.022
Gastrin-17 (μg/L)
0.573
Data are expressed as the mean with standard deviation or number (%), where appropriate. During WMT, an endoscopic administration tube was placed in the stomach (or upper) or jejunum (or middle) through the upper gastrointestinal tract or right hemicolon (or lower) through the lower gastrointestinal tract. , compared between patients receiving WMT via middle gastrointestinal tract delivery route alone and those with lower gastrointestinal tract delivery route alone. IBS: irritable bowel syndrome; NAFLD: nonalcoholic fatty liver disease; HE: hepatic encephalopathy; GERD: gastroesophageal reflux disease; GA: gouty arthritis; AH: alcoholic hepatitis; HC: hepatic cirrhosis; FD: functional dyspepsia; ADHD: attention deficit hyperactivity disorder; PG: pepsinogen.
