Research Article

A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy

Table 1

Baseline characteristics.

Group A ()Group B ()Group C () value

Strict food restriction (no. (%))25 (25.3%)29 (29.3%)22 (22.7%)0.565
Age ( (years))0.140
Height ( (m))0.209
Weight ( (kg))0.941
BMI ( (kg))0.277
Comorbidities (no. (%))
 Hypertension31 (31.3%)28 (28.3%)32 (33.0%)0.770
 Diabetes mellitus13 (13.1%)12 (12.1%)17 (17.5%)0.517
 Cardiovascular disease10 (10.1%)11 (11.1%)8 (8.2%)0.792
 Others33 (33.3%)29 (29.3%)25 (25.8%)0.509
Indication for colonoscopy
 Screening/surveillance55 (56.1%)50 (50.5%)60 (61.9%)0.278
 History of colon polyp22 (22.2%)24 (24.2%)20 (20.6%)0.830
 Abdominal pain5 (5.1%)10 (10.1%)4 (4.1%)0.184
 Overt intestinal bleeding1 (1.0%)1 (1.0%)2 (2.1%)0.764
 Occult blood in stool1 (1.0%)2 (2.0%)1 (1.0%)0.782
 Loose stool4 (4.0%)2 (2.0%)6 (6.2%)0.336
 Anemia2 (2.0%)2 (2.0%)2 (2.1%)1.000
 Others9 (9.0%)8 (8.0%)5 (5.2%)0.855
Constipation14 (14.1%)16 (16.2%)16 (16.3%)0.895
Education (more than high school education)69 (69.7%)59 (59.6%)64 (65.3%)0.328
Currently single (unmarried/divorced/bereaved)28 (28.3%)33 (33.3%)27 (27.6%)0.626
Time interval from previous colonoscopy (years)4.203.763.700.845

Group A: 2 L PEG-ASc; Group B: 1 L PEG-ASc plus bisacodyl; Group C: SP-MC plus bisacodyl; SD: standard deviation; BMI: body mass index. Constipation was defined as a defecation frequency of less than once every 3 days.