p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms

Figure 3

The relationship between histological subtypes and p53 IHC pattern in GI-NENs. (a, b) A case of well-differentiated NET with wild-type TP53 and pattern B of p53 expression (40x). (c, d) A poorly differentiated NEC case with TP53 missense mutation and pattern C2 (40x).

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