Prognostic Value of Inflammatory and Tumour Markers in Small-Duct Subtype Intrahepatic Cholangiocarcinoma after Curative-Intent Resection

Table 3

Univariate analysis of prognostic factors for small-duct type ICC in the training cohort.

Variables	DFS			OS
	HR	95% CI	value	HR	95% CI	value
Platelet (10^9/L)	1.185	0.574-2.447	0.646	0.646	0.287-1.455	0.292
(<165 vs. ≥165)
Neutrophil (10^9/L)	2.033	1.143-3.576	0.015	1.976	0.954-4.090	0.067
(<4.15 vs. ≥4.15)
Lymphocyte (10^9/L)	0.495	0.281-0.872	0.015	0.476	0.231-0.982	0.044
(<1.60 vs. ≥1.60)
Monocyte (10^9/L)	1.061	4.495-2.273	0.878	1.496	0.567-3.949	0.416
(<0.54 vs. ≥0.54)
NLR	1.877	0.949-3.714	0.071	2.642	1.161-6.019	0.021
(<3.00 vs. ≥3.00)
LMR	0.394	0.152-1.021	0.055	0.218	0.070	0.008
(<2.70 vs. ≥2.70)
PLR	1.791	0.889-3.608	0.103	0.862	0.395-1.883	0.710
(<90.0 vs. ≥90.0)
PII	2.367	1.186-4.724	0.014	3.127	1.420-6.886	0.005
(<1.50 vs. ≥1.50)
CEA (ug/L)	2.383	1.229-4.619	0.010	1.731	0.698-4.292	0.236
(<4.50 vs. ≥4.50)
CA19-9 (U/ml)	2.956	1.586-5.508	0.001	2.858	1.287-6.347	0.010
(<76.0 vs. ≥76.0)
CA242 (IU/ml)	3.254	1.544-6.859	0.002	2.073	0.779-5.516	0.145
(<30.0 vs. ≥30.0)
Ferritin (ug/L)	2.466	1.270	0.008	4.391	1.658-11.629	0.003
(<150.0 vs. ≥150.0)