Research Article
Intrahepatic Cholestasis of Pregnancy and Associated Adverse Maternal and Fetal Outcomes: A Retrospective Case-Control Study
Table 3
Adverse effects in ICP and controls (
(%)).
| | Control () | ICP () | Univariate analysis | Multivariate analysis | | OR | 95% CI | value | aOR | 95% CI | value |
| | Preeclampsia | 4 (0.70) | 12 (10.53) | 16.65 | 5.27-52.63 | | 16.74 | 5.29-52.98 | | | Cesarean section | 125 (21.93) | 40 (35.09) | 1.92 | 1.25-2.97 | | 1.76 | 1.10-2.81 | | | GDM | 117 (20.53) | 21 (18.42) | 0.87 | 0.52-1.46 | 0.61 | — | — | — | | Polyhydramnios | 2 (0.35) | 0 (0) | 0.00 | 0.00 | 1.00 | — | — | — | | Oligohydramnios | 5 (0.88) | 1 (0.88) | 1.00 | 0.12-8.64 | 1.00 | — | — | — | | Postpartum hemorrhage | 4 (0.70) | 0 (0) | 0.00 | 0.00 | 1.00 | — | — | — | | Puerperal infection | 4 (0.70) | 0 (0) | 0.00 | 0.00 | 1.00 | — | — | — | | Preterm birth | 1 (0.18) | 7 (6.14) | 37.22 | 4.53-305.64 | | 24.35 | 2.74-216.67 | | | Macrosomia | 16 (2.81) | 3 (2.63) | 0.94 | 0.27-3.27 | 0.92 | — | — | — | | Fetal distress | 5 (0.88) | 3 (2.63) | 3.05 | 0.72-12.97 | 0.13 | — | — | — | | Fetal malformation | 1 (0.18) | 0 (0) | 0.00 | 0.00 | 1.00 | — | — | — | | Stillbirth | 0 (0) | 0 (0) | — | — | — | — | — | — |
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ICP—patients with . ICP: intrahepatic cholestasis of pregnancy; GDM: gestational diabetes mellitus. |
