Serum Lactate Dehydrogenase Is a Sensitive Predictor of Systemic Complications of Acute Pancreatitis

Table 5

Binary logistic regression analyses of elevated LDH (>290 U/L) as a risk factor for AP complications and interventions.

	OR (95% CI)	P-value
Complications
Pleural effusion	1.906 (1.057–3.438)	0.032
Ascitic fluid	2.594 (1.173–5.736)	0.019
Myocardial infarction	143,143,341.1 (0.000–)	0.996
SIRS	3.887 (2.049–7.376)	<0.001
AKI	4.277 (1.656–11.042)	0.003
Acute respiratory failure	—	—
Acute heart failure	3.434 (0.850–13.875)	0.083
Interventions
Diuretic agent use	2.516 (1.207–5.247)	0.014
Vasoactive agent use	7.285 (1.420–37.381)	0.017
Tracheal intubation	2,709,293,434 (0.000 7.339E+263)	0.942
Pancreatic surgery	—	—
Transfer to intensive care unit	—	—

Analyses were adjusted for gender, age, hypocalcemia, and serum lipase, amylase, glucose, alanine aminotransferase, and aspartate aminotransferase. The normal LDH group served as the reference group. AKI, acute kidney injury; AP, acute pancreatitis; CI, confidence interval; OR, odds ratio; SIRS, systemic inflammatory response syndrome.