Expression of TRP Channels in Colonic Mucosa of IBS-D Patients and Its Correlation with the Severity of the Disease

Figure 3

Expression of TRPA1 and TRPV4 was increased in the colonic mucosa of IBS-D patients and TRPA1 content correlated with the severity of the disease. (a, b) The expression of TRPA1 in the colonic mucosa of IBS-D patients was increased compared with HCs. (c) TRPA1 content correlated positively with the disease severity. (d, e) The expression of TRPV4 was enhanced in the colonic biopsies of IBS-D patients. (f) TRPV4 expression did not correlate with the disease severity. Scale bar, 50 μM. , .

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