Neutrophil-Lymphocyte Ratio in Patients with Hypertriglyceridemic Pancreatitis Predicts Persistent Organ Failure
Table 1
Demographic and clinical characteristics according to the occurrence of POF.
Variables
Total()
Non-POF()
POF()
Demographics and comorbidities
Age, median (IQR), years
38 (32-47)
39 (32-47)
36 (31-43)
0.084
Male sex, (%)
325 (72.9)
255 (71.4)
70 (78.7)
0.17
BMI, median (IQR), kg/m2
27.0 (24.3-29.7)
26.9 (24.2-29.4)
27.7 (24.8-30.1)
0.227
Current smoker, (%)
160 (35.9)
125 (35.0)
35 (39.3)
0.448
Alcohol drinker, (%)
127 (28.5)
104 (29.1)
23 (25.8)
0.538
Prior acute pancreatitis, (%)
213 (47.8)
179 (50.1)
34 (38.2)
0.044
Diabetes mellitus, (%)
140 (31.4)
112 (31.4)
28 (31.5)
0.987
Hyperlipidemia, (%)
228 (51.1)
183 (51.3)
45 (50.6)
0.906
Hypertension, (%)
90 (20.2)
70 (19.6)
20 (22.5)
0.547
Time from pain onset to admission, median (IQR), hours
9.0 (5.3-20.0)
8.1 (5.0-18.0)
17.0 (7.7-28.2)
<0.001
Laboratory data at admission
White blood cells, median (IQR), ×109/L
13.1 (10.3-15.8)
12.8 (10.3-15.3)
14.9 (10.8-17.2)
0.006
Hematocrit, median (IQR), %
44.5 (40.4-47.4)
44.0 (40.0-46.8)
45.6 (41.7-49.0)
0.003
Platelet, median (IQR), ×109/L
225 (177-268)
227 (177-268)
211 (178-269)
0.357
Neutrophil, median (IQR), ×109/L
10.6 (8.2-13.5)
10.4 (8.1-12.9)
12.9 (8.7-14.6)
0.002
Lymphocyte, median (IQR), ×109/L
1.60 (1.20-2.10)
1.60 (1.30-2.20)
1.40 (1.00-1.88)
0.006
NLR
6.56 (4.39-10.3)
6.17 (4.25-9.55)
8.51 (6.25-16.0)
<0.001
PLR
135 (102-192)
133 (101-184)
144 (103-212)
0.154
Triglyceride, median (IQR), mmol/L
20.6 (13.6-39.6)
19.8 (12.9-37.2)
26.7 (15.7-44.8)
0.005
Calcium, median (IQR), mmol/L
2.37 (2.25-2.47)
2.39 (2.30-2.48)
2.15 (1.77-2.38)
<0.001
Urea, median (IQR), mmol/L
4.24 (3.35-5.30)
4.20 (3.34-5.08)
4.80 (3.36-5.99)
0.012
Albumin, median (IQR), g/L
44.4 (41.6-47.0)
44.9 (42.8-47.2)
40.4 (35.2-44.6)
<0.001
Glucose, median (IQR), mmol/L
9.85 (7.04-15.5)
9.19 (6.92-15.2)
12.5 (8.4-16.3)
0.001
CRP, median (IQR), mg/L
14.3 (4.35-76.9)
11.6 (3.4-50.5)
65.8 (9.8-269)
<0.001
Scoring systems
APACHE II score, median (IQR)
5 (3-8)
4 (2-7)
10 (7-12)
<0.001
Ranson’s score, median (IQR)
2 (1-3)
1 (1-2)
5 (3-6)
<0.001
SOFA score, median (IQR)
1 (0-2)
1 (0-1)
2 (2-3)
<0.001
BISAP score, median (IQR)
1 (0-1)
1 (0-1)
2 (1-2)
<0.001
APACHE: acute physiology and chronic health evaluation; BISAP: bedside index of severity in acute pancreatitis; BMI: body mass index; CRP: C reactive protein; IQR: interquartile range; NLR: neutrophil-lymphocyte ratio; PLR: platelet-lymphocyte ratio; POF: persistent organ failure; SOFA: sequential organ failure assessment.
