Efficacy and Safety of Endoscopic Resection for Small Gastric Gastrointestinal Stromal Tumors in Elderly Patients
Table 2
Clinicopathological characteristics of gastric GISTs.
Characteristics
Nonelderly (<65 years)
Elderly (≥65 years)
value
Number of patients
195
65
Number of lesions
199
66
Tumor location
NS
Gastric cardia
6 (3.0%)
3 (4.5%)
Gastric fundus
98 (49.3%)
32 (48.5%)
Gastric body
80 (40.2%)
30 (45.5%)
Gastric antrum
10 (5.0%)
1 (1.5%)
Anastomosis
5 (2.5%)
0 (0.0%)
Tumor size
NS
≤2 cm
137 (68.8%)
37 (56.1%)
2-5 cm
62 (31.2%)
29 (43.9%)
Tumor ulceration
8 (4.0%)
8 (12.1%)
0.017
Tumor margin
NS
Regular
199 (100.0%)
65 (98.5%)
Irregular
0 (0.0%)
1 (1.5%)
Morphology
NS
Spindle
194 (97.5%)
64 (97.0%)
Epithelioid
1 (0.5%)
0 (0.0%)
Mixed
4 (2.0%)
2 (3.0%)
Mitotic count
NS
≤5/50 HPF
189 (95.0%)
63 (95.5%)
6-10/50 HPF
6 (3.0%)
2 (3.0%)
>10/50 HPF
4 (2.0%)
1 (1.5%)
Growth pattern
NS
Intraluminal growth
153 (76.9%)
51 (77.3%)
Extraluminal growth
34 (17.1%)
13 (19.7%)
Mixed
12 (6.0%)
2 (3.0%)
Modified NIH risk categories
NS
Very low risk
85 (42.7%)
20 (30.3%)
Low risk
101 (50.8%)
41 (62.1%)
Intermediate risk
9 (4.5%)
4 (6.1%)
High risk
4 (2.0%)
1 (1.5%)
IHC
CD34 (+)
195 (98.0%)
64 (97.0%)
NS
CD117 (+)
199 (100.0%)
65 (98.5%)
NS
DOG-1 (+)
196 (98.5%)
66 (100.0%)
NS
Data are shown as (%) or mn of patients. NS: not significant; IHC: immunohistochemistry; CD34: CD34 protein; CD117: CD117 protein; DOG1: DOG1 protein; HPF: high-power field; NIH: National Institutes of Health.
