Gastroenterology Research and Practice / 2023 / Article / Tab 1 / Research Article
Clinical Distribution Characteristics and Identification for Significant Liver Inflammation of Patients in Chronic Hepatitis B with Indeterminate Phase Table 1 Clinical distribution characteristics of CHB patients with different immune states.
Variables Immune active Immune tolerant ( HBeAg positive ( Inactive ( HBeAg negative ( Indeterminate phase ( Age (year) 32.0 (27.0–40.0) 30.0 (26.0–37.0) 42.0 (34.0–49.0) 41.0 (37.0–47.0) 41.0 (34.0–48.0) <0.001 Sex (male%) 135 (52.1%) 260 (71.2%) 76 (59.4%) 28 (84.8%) 284 (56.2%) <0.001 WBC (×109 /L) 5.7 (4.7–6.9) 5.4 (4.6–6.4) 5.7 (4.6–6.4) 5.8 (4.5–6.9) 5.4 (4.5–6.6) 0.241 PLT (×109 /L) 198.0 (170.0–228.0) 189.0 (154.5–223.0) 189.0 (147.3–223.0) 182.0 (133.0–222.5) 174.0 (144.0–210.0) <0.001 PT (s) 11.6 (11.1–12.1) 11.6 (11.1–12.2) 11.4 (11.0–12.0) 11.4 (10.8–11.8) 11.6 (11.1–12.2) 0.025 INR 1.0 (1.0–1.1) 1.0 (1.0–1.1) 1.0 (1.0–1.1) 1.0 (0.9–1.0) 1.0 (1.0–1.1) 0.002 ALB (g/L) 45.0 (42.3–47.5) 45.0 (42.2–47.5) 44.8 (43.2–46.7) 45.3 (43.1–48.1) 44.8 (42.2–47.3) 0.766 GLB (g/L) 28.4 (25.3–30.6) 28.5 (25.7–31.3) 28.0 (28.8–31.0) 28.2 (26.5–30.7) 28.1 (25.5–31.6) 0.875 ALT (U/L) 26.0 (19.0–32.0) 71.0 (53.0–111.0) 21.5 (15.3–30.5) 55.0 (47.0–86.5) 33.0 (22.0–54.0) <0.001 AST (U/L) 24.0 (20.0–28.0) 44.0 (35.0–65.5) 23.0 (19.0–28.0) 36.0 (31.0–59.5) 29.0 (23.0–39.0) <0.001 GGT (U/L) 16.0 (12.0–22.0) 30.0 (20.0–49.0) 17.5 (13.0–30.0) 36.0 (23.5–56.0) 23.0 (15.0–35.5) <0.001 ALP (U/L) 68.0 (57.0–83.0) 78.0 (64.0–93.0) 71.5 (60.0–85.3) 84.0 (74.0–95.0) 78.0 (62.0–96.0) <0.001 TBIL (μ mol/L) 13.0 (9.2–16.6) 14.0 (11.0–18.2) 15.3 (11.8–18.1) 15.7 (13.0–18.0) 14.0 (10.8–18.2) 0.002 Log10 (HBV-DNA IU/ml) 7.9 (7.3–8.4) 7.5 (6.7–8.2) 2.8 (2.4–3.1) 2.6 (2.3–3.1) 4.3 (3.7–5.3) <0.001 Log10 (HBsAg IU/ml) 2.4 (2.4–4.7) 3.4 (2.4–4.5) 2.4 (2.3–2.4) 2.4 (1.9–2.4) 2.4 (2.4–3.3) <0.001 Anti-HBC (S/CO) <0.001 Liver inflammation (%) 0 4 (1.5) 1 (0.3) 2 (1.6) 2 (6.1) 2 (0.5) <0.001 1 166 (64.1) 162 (44.4) 90 (70.3) 18 (54.5) 200 (45.4) 2 81 (31.3) 152 (41.6) 33 (25.8) 11 (33.3) 188 (42.6) 3 8 (3.1) 47 (12.9) 3 (2.3) 2 (6.1) 45 (10.2) 4 0 (0) 3 (0.8) 0 (0) 0 (0) 6 (1.4) Fibrosis (%) 0 69 (26.6) 49 (13.4) 13 (10.4) 2 (6.1) 67 (15.2) <0.001 1 121 (46.7) 174 (47.7) 55 (44.0) 11 (33.3) 161 (36.5) 2 56 (21.6) 90 (24.7) 44 (35.2) 19 (57.6) 122 (27.7) 3 7 (2.7) 29 (7.9) 9 (7.2) 1 (3.0) 48 (10.9) 4 6 (2.3) 23 (6.3) 7 (5.6) 0 (0) 43 (9.7)
