Large Region of Homozygous (ROH) Identified in Indian Patients with Autosomal Recessive Limb-Girdle Muscular Dystrophy with p.Thr182Pro Variant in SGCB Gene

Table 1

Frequency of 7 markers with alternative allele as major allele found in common ROH region.

Chrom	Position (GRCh38)	rsid	Ref-base	Alt-base	Case ()	Control ()	value	Population level databases
								gnomAD v3.1.2	1000G	GA100K
4	51817441	rs1910739	T	C	0.8529	0.5586	<0.0001	0.3659	0.5306	0.5023
4	51818654	rs2874073	A	C	0.8529	0.8398	0.7717	0.8694	0.8970	0.8907
4	51918512	rs6852236	A	G	0.8529	0.5664	<0.0001	0.4132	0.5164	0.5181
4	52102311	rs13122418	G	A	0.8529	0.6250	<0.0001	0.6235	0.5445	0.5941
4	52117235	rs11133358	A	G	0.8529	0.9883	0.4599	0.8038	0.7859	0.9543
4	52195229	rs13353646	C	T	0.8529	0.3945	<0.0001	0.1746	0.1933	0.2177
4	52269957	rs6554360	C	T	0.8382	0.6094	<0.0001	0.4297	0.4860	0.5800