Research Article
Genotype and Phenotype Characteristics of Chinese Pediatric Patients with Primary Hyperoxaluria
Table 1
Comparisons of phenotypes among PH1, PH2, and PH3 patients.
| | Variables | PH1 () | PH2 () | PH3 () | |
| | Age of onset (years) | 5 (0.3, 11) () | 8 (1, 13) () | 1 (0.3, 6) () | <0.001 | | Nephrocalcinosis (%) | 66.67% () | 42.86% () | 23.53% () | 0.105 | | eGFR (ml/min/1.73 m2) | () | () | () | 0.807 | | Urine oxalate/creatinine ratio (μg/mg) () | 457.9 (34.02, 1860.88) () | 182.38 (1.79, 414.24) () | 309.14 (18.57, 1470.16) () | 0.189 | | Urine calcium/creatinine ratio (mmol/mmol) () | 0.19 (0.06, 1.13) () | 0.21 (0.02 0.41) () | 0.32 (0.12, 2.43) () | 0.096 | | Urine citrate/creatinine ratio (μg/mg) () | 91.81 (48.79, 502.38) () | 85.56 (13.95, 184.78) () | 163.9 (46.61, 645.4) () | 0.044 | | Residual stones (%) | 69.23% () | 57.14% () | 0% () | <0.001 | | Stone recurrence (%) | 100% () | 100% () | 25% () | <0.001 |
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Abbreviations: nL: normal limit; eGFR: estimated glomerular filtration rate. . |
