The Association of Heterozygous p.R4810K of RNF213 and Long-Term Unfavorable Outcomes after Encephaloduroarteriosynangiosis in Chinese Pediatric Patients with Moyamoya Disease

Figure 2

Correlation between the clinical phenotype of long-term unfavorable outcomes among three pediatric patient groups with different genotypes (AA, GA, and GG) and RNF213 p.R4810K genotype. (a) The violin chart plot of age at onset for three pediatric patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant in moyamoya disease. (b) The violin chart plot of initial mRS for three pediatric patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant in moyamoya disease. (c) The cumulative initial infarction incidence curve of MMD in three patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant. (d) The cumulative initial hematoma incidence curve of MMD in three patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant. (e) The cumulative waiting infarction incidence curve of MMD in three patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant. (f) The cumulative infarction during follow-up incidence curve of MMD in three patient groups with different genotypes (AA, GA, and GG) of the p.R4810K variant.

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