Human Mutation / 2024 / Article / Tab 3 / Research Article
The Association of Heterozygous p.R4810K of RNF213 and Long-Term Unfavorable Outcomes after Encephaloduroarteriosynangiosis in Chinese Pediatric Patients with Moyamoya Disease Table 3 Univariate and logistic regression analyses of risk factors for unfavorable outcome (final
).Variables OR [95% CI] valueGender (ref: male) 1.08 [0.52-2.25] 0.833 Age at onset 0.87 [0.79-0.97] 0.009 Onset with infarction 1.37 [0.58-3.25] 0.474 Onset with hematoma 17.44 [4.9-62.07] <0.001 Onset → operation (ref: <2 mons) 0.44 [0.2-0.97] 0.042 p.R4810K GA (ref: GG) 1.17 [0.54-2.5] 0.692 Hyperlipidemia 1.01 [0.28-3.61] 0.988 Hyperhomocysteinemia 1.37 [0.29-6.54] 0.695 Family history 2.12 [0.55-8.14] 0.274 Laterality (ref: unilateral) 1.04 [0.12-8.75] 0.97 Waiting infarction 4.94 [2.26-10.77] <0.001 Initial mRS (ref: <2) 38.36 [14.93-98.61] <0.001 Unilateral PCA involvement 1.6 [0.61-4.24] 0.34 Bilateral PCA involvement 2.13 [0.88-5.17] 0.095 Suzuki stage (ref: <4) 1.48 [0.67-3.27] 0.329 Perioperative infarction 22.1 [2.23-219.35] 0.008 Infarction during follow-up 4.34 [0.99-19.09] 0.052
Abbreviations: CI: confidence interval; OR: odds ratio; PCA: posterior cerebral artery; mRS: modified Rankin scale.