Disruption of <i>OVOL2</i> Distal Regulatory Elements as a Possible Mechanism Implicated in Corneal Endothelial Dystrophy

<div>Visualization of topologically associated domains (TADs) at chr20p11.23 in neural progenitor cells (H1 NPCs). Interaction heat maps, in which TADs are indicated as triangles using (a) DI and (b) TopDom algorithms. The position of the breakpoint is highlighted with a red bar. (c) Gene annotation (MANE transcripts), <i>OVOL2</i> is shown embedded in a red box.</div>

Human Mutation

fig3

Figure 3

Figure 3: Disruption of <i>OVOL2</i> Distal Regulatory Elements as a Possible Mechanism Implicated in Corneal Endothelial Dystrophy 

Human Mutation

Disruption of OVOL2 Distal Regulatory Elements as a Possible Mechanism Implicated in Corneal Endothelial Dystrophy

Figure 3