Research Article
The Missing Piece of the Puzzle: Unveiling the Role of PTPN11 Gene in Multiple Osteochondromas in a Large Cohort Study
Table 1
Summary of clinical data from 244 probands from unrelated families.
| | Male | Female | Total |
| | Number | 146 | 98 | 244 | | Sporadic cases | 64 | 42 | 106 | | Familial cases | 70 | 51 | 121 | | Unknown family history | 12 | 5 | 17 | | Age of last examination (median, IQR) | 9 (5-15) | 10.5 (6-25) | 10 (5.25-16) | | Availability of clinical data for IOR scale | 134 | 92 | 226 | | Not sufficient clinical data for IOR scale | 12 | 6 | 18 | | Localization of first OC | 122 | 78 | 200 | | Unknown localization | 24 | 20 | 44 | | Age of discovery of 1st OC | 118 | 75 | 193 | | Unknown age of discover of 1st OC | 28 | 23 | 51 |
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IQR: interquartile range; IOR: clinical scale of severity of MO by the Istituto Ortopedico Rizzoli.
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