Practical Recommendations for the Selection of Patients for Individualized Splice-Switching ASO-Based Treatments

<div>Decision tree for variant evaluation of exonic LoF variants not disrupting splicing. The aim of this decision tree is to identify exonic LoF variants that can be targeted with a ssASO via exon skipping.</div>

Human Mutation

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Figure 2

Figure 2: Practical Recommendations for the Selection of Patients for Individualized Splice-Switching ASO-Based Treatments 