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Author | Country | Outcomes of cholera in pregnancy | Risk factors of cholera in fetus |
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Ciglenecki et al. [18], Schillberg et al. [17] | Haiti | 86% of pregnant women were discharged with a preserved pregnancy, and 6% had live full-term singleton births, of whom 2 died within the first 5 days postpartum. The remaining pregnancies (8%) resulted in intrauterine fetal death [18] | The strongest risk factor for fetal death was severe maternal dehydration, followed by severe vomiting Risk factors for complications of cholera in pregnant women were third trimester, younger maternal age, severe dehydration, and vomiting [17] |
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Nguyen-Toan Tran et al. [8] | Switzerland | The pooled maternal death rate for 1991-2013 studies was 0.2% (95% CI: 0.0-0.7) and 5.0% (95% CI: 0.0-16.0) for 1969-1990 | The pooled fetal death rate for 4 studies during 1991-2013 was 7.9%, significantly lower than that of 3 studies from 1969 to 1990 |
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Grout et al. [20], Moro et al. [16], Ali et al. [13], Davis et al. [5], and Wierzba et al. [19] | USA | Pregnant women are at risk of severe diarrheal disease that can result in dehydration and pregnancy loss [16] They are at risk of premature childbirth, or maternal death if the patient is not treated properly [13], fetal acidosis and hypoxia [5], and fetal distress and death [19] | Fetal malformations |
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Zhang et al. [21] | China | NA | There was no association of pregnant women infected with cholera with an increased risk of preterm delivery, low birthweight, accidental abortion, or malformation |
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Khan et al. [15], Khan et al. [12] | Bangladesh | Pregnancy loss with magnitude varying from 2 to 36% Adverse outcomes of pregnancy with infection of cholera | No association |
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Hashim et al. [14] | Korea | Abortions, premature childbirth, and maternal death | No association |
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Friedrich et al. [22] | Malawi | Miscarriage and stillbirths | No association |
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