Research Article

A Fast and Validated HPLC Method for the Simultaneous Analysis of Five 5-HT3 Receptor Antagonists via the Quantitative Analysis of Multicomponents by a Single Marker

Figure 3

Typical HPLC chromatogram for simultaneous separation of ODT, GNT, TPT, AZT, and RMT. Chromatographic conditions were acetonitrile-0.05 mol·L−1 potassium dihydrogen phosphate (phosphoric acid to adjust pH to 4.0), except the acetonitrile content was varied: (a) acetonitrile content 20; (b) acetonitrile content 25; (c) acetonitrile content 30; and (d) acetonitrile content 35.