Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Vardenafil and Its Application of Bioequivalence

<table class="table-group" id="tab5"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left"> </td><td class="align_center">LQC (AUC ratio)</td><td class="align_center">HQC (AUC ratio)</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Mean</td><td class="align_center">1.22</td><td class="align_center">1.30</td></tr><tr><td class="align_left">SD</td><td class="align_center">0.04</td><td class="align_center">1.46</td></tr><tr><td class="align_left">RSD %</td><td class="align_center">3.59</td><td class="align_center">4.38</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>SD: standard deviation; RSD: relative standard deviation; %: percentage; LQC: low quality control; MQC: medium quality control; <i>n</i> = 6.<br/></div></td></tr></table>

<div>Matrix effect of vardenafil in plasma.</div>

International Journal of Analytical Chemistry

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Table 5

Table 5: Liquid Chromatography-Tandem Mass Spectrometry Method for the Determination of Vardenafil and Its Application of Bioequivalence 