Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS

Table 1

Main mass spectral parameters of pemetrexed and IS.

Name	Ionization type	Precursor ions (m/z)	Fragmentor (V)	Collision energy (eV)	Product ions (m/z)
Pemetrexed	＋	428.3	80	10	281.2
Nilotinib (IS)	＋	530.2	130	32	289.2