Research Article
Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS
Table 3
Interprecision and intraprecision and accuracy of pemetrexed (n = 5).
| | Analyte | Nominal concentration (ng/mL) | Intraday | Interday | | Measured concentration (ng/mL, mean ± SD) | Precision (RSD%) | Accuracy (RE%) | Measured concentration (ng/mL, mean ± SD) | Precision (RSD%) | Accuracy (RE%) |
| | Pemetrexed | 2 | 1.74 ± 0.40 | 14.12 | 92.49 | 1.70 ± 0.28 | 14.67 | 85.19 | | 5 | 4.84 ± 0.65 | 13.43 | 96.78 | 4.50 ± 0.60 | 13.40 | 90.08 | | 20 | 19.15 ± 0.70 | 3.63 | 95.76 | 17.34 ± 1.58 | 9.09 | 86.71 | | 100 | 100.51 ± 3.14 | 3.12 | 100.51 | 98.21 ± 2.94 | 2.99 | 98.21 |
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