HPLC Analytical Method Development and Validation of Gabapentin through Chemical Derivatization with Catechol as a Chromophore

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Concentration (mg/mL)</td><td class="align_center">AUC</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left" rowspan="3">0.5</td><td class="align_center">17755412</td></tr><tr><td class="align_center">17653532</td></tr><tr><td class="align_center">17749442</td></tr><tr><td class="align_center" colspan="2">RSD = 0.32</td></tr><tr><td class="align_left" colspan="2"><hr/></td></tr><tr><td class="align_left" rowspan="3">1</td><td class="align_center">28957831</td></tr><tr><td class="align_center">28857921</td></tr><tr><td class="align_center">29357939</td></tr><tr><td class="align_center" colspan="2">RSD = 0.91</td></tr><tr><td class="align_left" colspan="2"><hr/></td></tr><tr><td class="align_left" rowspan="3">2.5</td><td class="align_center">83217465</td></tr><tr><td class="align_center">83917561</td></tr><tr><td class="align_center">83617467</td></tr><tr><td class="align_center" colspan="2">RSD = 0.42</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

International Journal of Analytical Chemistry

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Table 3

Table 3: HPLC Analytical Method Development and Validation of Gabapentin through Chemical Derivatization with Catechol as a Chromophore 