Research Article
HPLC Analytical Method Development and Validation of Gabapentin through Chemical Derivatization with Catechol as a Chromophore
Table 4
Robustness and ruggedness test.
| | Condition | AUC |
| | Analyst 1 | 63175584 | | 63571712 | | Analyst 2 | 63296473 | | 63342018 | | Flow rate 0.9 mL/min | 64366812 | | 63366720 | | Flow rate 1.1 mL/min | 63562420 | | 63456610 | | Mobile phase 55% water | 63366810 | | 63499192 | | Mobile phase 45% water | 63398281 | | 63942653 | | Wavelength 302 nm | 63489294 | | 63933653 | | Wavelength 298 nm | 63387594 | | 63476709 | | Average | 63539533.44 | | SD | 300227.13 | | RSD | 0.47 |
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