Review on Characterization, Properties, and Analytical Methods of Cefepime

Table 3

Potentiometric and electrochemical methods for assay of CP.

Technique’s name	Solvents/Conditions	Matrices	Reference
PH potentiometry	264 and 230; Dilution with UB (0.1 M CH3COOH + 0.1 MH3PO4 + 0.1 MH3BO3)	Pharmaceutical preparation	[57]
Electrochemical reduction and oxidation	WE (glassy carbon electrode), RE (AgCl), AE (platinum wire); The solutions were prepared in water and diluted with electrolytes	Pharmaceutical preparation	[58]
Electrochemical Reduction	A saturated AgCl (RE), WE (dropping mercury electrode), AE (glassy carbon) PB pH 2.7 (adjusted by 1 MH3PO4 + 1 M NaOH)	Pharmaceutical formulations and human urine samples	[59]
ASV + DPP	RE (Ag/AgCl/saturated KC), WE (dropping-mercury electrode), AE (platinum wire); For urine or plasma (PB pH 5.8), for serum (1 MH3PO4 and 1 M KOH pH 2.7) 0.1 M KCl used as ionic strength	Human urine, cerebrospinal fluid, and Serum	[60]