Pharmacokinetic Difference of Six Active Constituents of Huangqi Liuyi Decoction between Control and Diabetic Nephropathy Mouse Models

Table 2

Calibration curve of six analytes in mouse plasma.

Analyte	Linear regression equation	r	Linear range (ng/mL)	LLOQ (ng/mL)	LOD (ng/mL)
Astragaloside IV	Y = 0.0025X + 0.3926	0.9993	10.68–2670	10.68	0.33
Calycosin-7-O-β-D-glucoside	Y = 0.0375X + 0.9606	0.9995	5.05–505	5.05	0.01
Calycosin-glucuronide	Y = 0.0208X + 0.4845	0.9995	5.19–2595	5.19	0.03
Formononetin	Y = 0.0043X + 0.1080	0.9992	2.62–523	2.62	0.03
Ononin	Y = 0.0033X + 0.1591	0.9990	5.07–1014	5.07	0.07
Glycyrrhizic acid	Y = 0.0109X + 0.5029	0.9995	5.09–3817	5.09	0.04