Research Article

Pharmacokinetic Difference of Six Active Constituents of Huangqi Liuyi Decoction between Control and Diabetic Nephropathy Mouse Models

Table 3

Intra- and interday precision and accuracy of six analytes in mouse plasma ( ± SD, n = 6).

AnalyteConcertation of analyte (ng/mL)Mean ± SD (ng/mL)Accuracy (%)Interday precision RSD (%)Intraday precision RSD (%)

Astragaloside IV16.0215.01 ± 0.6693.68 ± 6.714.428.47
801813.9 ± 74.06101.6 ± 1.999.106.56
16021522 ± 107.3395.03 ± 7.207.057.08

Calycosin-7-O-β-D-glucoside15.1515.59 ± 1.55102.9 ± 5.239.948.92
75.7567.65 ± 5.5189.31 ± 7.568.145.39
151.5157.8 ± 5.67104.2 ± 7.833.596.70

Calycosin-glucuronide10.388.57 ± 0.4882.57 ± 1.912.315.57
519492.9 ± 23.5694.98 ± 9.154.786.10
1038927.5 ± 81.6289.35 ± 7.038.805.27

Formononetin5.235.02 ± 0.4495.97 ± 8.328.676.41
261.5266.6 ± 19.86101.9 ± 7.597.457.59
313.8307.4 ± 41.0297.83 ± 10.1813.357.10

Ononin10.419.35 ± 0.7792.24 ± 5.938.227.61
507445.8 ± 32.6387.93 ± 5.117.3210.16
10141051 ± 60.94103.6 ± 6.965.804.40

Glycyrrhizic acid12.7311.89 ± 1.393.40 ± 10.2410.963.22
12731046 ± 62.9982.23 ± 1.341.625.28
25452525 ± 142.1599.21 ± 3.965.634.38