Pharmacokinetic Difference of Six Active Constituents of Huangqi Liuyi Decoction between Control and Diabetic Nephropathy Mouse Models

Table 4

Extraction recovery and matrix effect of six analytes in mouse plasma ( ± SD, n = 6).

Analyte	Concertation of analyte (ng/mL)	Extraction recovery (%)	RSD %	Matrix effect (%)	RSD %
Astragaloside IV	16.02	99.78 ± 7.56	7.58	87.11 ± 6.52	7.48
	801	106.1 ± 8.53	8.04	94.20 ± 9.33	9.90
	1602	112.7 ± 6.14	5.44	85.36 ± 3.49	4.08
Calycosin-7-O-β-D-glucoside	15.15	91.18 ± 3.46	3.80	83.04 ± 2.79	3.35
	75.75	89.05 ± 9.37	10.52	90.46 ± 4.80	5.31
	151.5	94.7 ± 4.23	4.46	101.9 ± 6.78	6.65
Calycosin-glucuronide	10.38	96.56 ± 8.59	8.89	86.86 ± 4.76	5.48
	519	82.39 ± 1.27	1.54	107.90 ± 10.01	9.27
	1038	110.9 ± 7.38	6.66	91.45 ± 7.41	8.11
Formononetin	5.23	103.1 ± 8.40	8.15	90.86 ± 6.58	7.24
	261.5	88.54 ± 5.65	6.38	93.47 ± 7.60	8.13
	313.8	102.8 ± 9.73	9.47	99.22 ± 7.79	7.85
Ononin	10.41	87.28 ± 6.74	7.73	104.42 ± 10.60	10.15
	507	98.92 ± 11.01	11.13	85.95 ± 3.69	4.29
	1014	86.36 ± 4.19	4.85	103.38 ± 10.49	10.15
Glycyrrhizic acid	12.73	90.03 ± 7.80	8.66	83.77 ± 1.92	2.29
	1272.5	95.35 ± 7.06	7.41	93.47 ± 7.60	8.13
	2545	89.83 ± 4.29	4.78	99.22 ± 7.79	7.85