A Validated RP-HPLC Method for Simultaneous Determination of Cefixime and Clavulanic Acid Powder in Pediatric Oral Suspension

Table 10

Robustness data of the proposed HPLC method for clavulanic acid.

Parameters		Avg. std. area (n = 6)	%RSD of std. area	Avg. sample area (n = 6)	%RSD of sample area	%assay (n = 6)	%RSD of assay
Flow rate	0.8 mL/min	690.375	0.0970	777.192	0.4834	99.74	0.5246
	1.2 mL/min	458.453	0.7325	519.788	0.6229	100.43	0.4519
pH	5.3	548.329	0.2196	620.548	0.1804	100.27	0.2610
	5.7	541.271	0.1995	610.756	0.3764	99.98	0.4910