A Validated RP-HPLC Method for Simultaneous Determination of Cefixime and Clavulanic Acid Powder in Pediatric Oral Suspension

Table 9

Robustness data of the proposed HPLC method for cefixime.

Parameters		Avg. std. area (n = 6)	%RSD of std. area	Avg. sample area (n = 6)	%RSD of sample area	%assay (n = 6)	%RSD of assay
Flow rate	0.8 mL/min	1446.738	0.0370	1179.034	0.2931	101.07	0.4145
	1.2 mL/min	958.232	0.1247	971.292	0.2592	99.65	0.3118
pH	5.3	1149.024	0.0992	1155.507	0.0380	98.86	0.1525
	5.7	1152.101	0.0962	1168.877	0.2503	99.74	0.2454