Research Article

Determination of Scopolamine Distribution in Plasma and Brain by LC-MS/MS in Rats

Table 2

Calibration curves and lower limits of quantification.

SampleLiner range (ng/mL)Regression equationrLLOQ (ng/mL)

Plasma2∼2500y = 0.01194x + 0.012490.9962
y = 0.01016x + 0.032440.994
y = 0.01305x + 0.002020.992

Brain homogenate2∼2500y = 0.01108x + 0.019980.9962
y = 0.01034x + 0.008900.993
y = 0.01095x + 0.007230.997