Comparative Pharmacokinetic Study of 5 Active Ingredients after Oral Administration of Zuogui Pill in Osteoporotic Rats with Different Syndrome Types

Table 2

Plasma concentrations of cAMP and cGMP in rats (n = 6).

Groups	cAMP (nmol/L)	cGMP (nmol/L)	cAMP/cGMP
Normal	101.7 ± 5.971	25.62 ± 3.176	3.901 ± 0.327
Osteoporosis	100.4 ± 3.302	26.46 ± 1.498	3.805 ± 0.233
Kidney-yang-deficiency	85.30 ± 5.061	35.84 ± 3.170	2.393 ± 0.234
Kidney-yin-deficiency	119.1 ± 9.349	23.20 ± 1.357	5.129 ± 0.509

and , according to t-test, versus osteoporosis rats.