Research Article
Comparative Pharmacokinetic Study of 5 Active Ingredients after Oral Administration of Zuogui Pill in Osteoporotic Rats with Different Syndrome Types
Table 3
Calibration curves, correlation coefficients, linear ranges, and LLOQs of 5 compounds.
| Compounds | Calibration curves | Correlation coefficients (r) | Linear range (ng/mL) | LLOQ (ng/mL) |
| Chlorogenic acid | y = 0.0226x − 0.0985 | 0.9997 | 1–1000 | 1 | Loganin | y = 0.0023x + 0.0297 | 0.9996 | 20–20000 | 20 | Morroniside | y = 0.0114x + 0.1404 | 0.9993 | 4–4000 | 4 | Aucubin | y = 0.0016x − 0.0175 | 0.9990 | 0.5–500 | 0.5 | Protocatechuic aldehyde | y = 0.1696x + 2.2261 | 0.9992 | 0.05–50 | 0.05 |
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