Evaluation of Antibiotics Residues in Milk and Meat Using Different Analytical Methods

Table 2

Antibiotic residues in different animal products.

Name of the antibiotic	Matrix	Extraction technique	Purification technique	Detection system	Recovery (%)	Reference
Tetracycline	Muscle	MSPD	Elution solvent: H2O (70°C)	LC-MS/MS	99–103	[86]
Tetracycline	Milk	LLE	SPE (oasis HLB)	LC-MS/MS	74–101	[87]
Tetracycline	Porcine kidney	MIPs	Elution solvent: MeOH : 1 M KOH (9 : 1, v/v)	HPLC-UV		[88]
Sulfonamide	Milk	LLE	Ultrafiltration	LC-MS/MS	90–125	[89]
Sulfonamide	Muscle	LLE	LLP (H2O: EtOAc)	UPLC-MS/MS	68–114	[90]
Quinolones	Bovine tissues	MSPD (sand)	Elution solvent: H2O (100°C)	LC-MS/MS	87–109	[91]
Quinolones	Milk	MSPD (sand)	Elution solvent: H2O (100°C)	LC-MS/MS	93–110	[77]
Quinolones	Eggs and tissue	MIPs	Elution solvent: ACN : TFA (99 : 1, v/v)	HPLC-FL	86–105	[92]
Aminoglycosides	Milk	MSPD (sand)	PLE	LC-MS/MS	70–92	[93]
Aminoglycosides	Muscle, liver	LSE	SPE (WCX)	LC-MS/MS	61–116	[94]
β-Lactams	Bovine kidney	LSE	DSPE (C18)	LC-MS/MS	58–75	[76]
β-Lactams	Milk	LLE	LLP	HPLC-UV	94–103	[95]
β-Lactams	Muscle	LSE	Ion-exchange SPE	LC-MS/MS	87–103	[96]