Research Article

The Determination of Polymyxin B in Critically Ill Patients by the HPLC-MS/MS Method

Table 4

Integrity of dilution of PB.

ComponentPB1PB2
Nominal conc. (ng/mL)Mean of found conc. (ng/mL)Mean of Acc. (%)CV (%)Nominal conc. (ng/mL)Mean of found conc. (ng/mL)Mean of Acc. (%)CV (%)

Dilution factor 21000010905109.12.01185.71192.4100.61.0
Dilution factor 41000010825108.23.71185.71199.8101.22.3