Research Article

Correlation between SMADs and Colorectal Cancer Expression, Prognosis, and Immune Infiltrates

Table 1

Correlation between immune cell infiltration and SMADs in CRC.

GenesSpearmanCells
B cellsCD8+ T cellsDCEosinophilsMacrophagesNeutrophils

SMAD1r0.2300.1900.1600.1900.2800.220
p<0.001<0.001<0.001<0.001<0.001<0.001

SMAD2r0.0490.2100.0370.0370.2900.130
p0.217<0.0010.3470.352<0.0010.001

SMAD3r0.0850.1200.0540.2000.0860.046
p0.0300.0020.170<0.0010.0290.246

SMAD4r0.1300.2300.1300.0840.3400.220
p0.001<0.0010.0010.032<0.001<0.001

SMAD5r−0.0620.050−0.150−0.0410.110−0.031
p0.1160.205<0.0010.2970.0050.436

SMAD6r0.004−0.0970.0890.032−0.310−0.170
p0.9100.0140.0240.417<0.001<0.001

SMAD7r0.2600.1700.1600.2600.1300.078
p<0.001<0.001<0.001<0.0010.0010.048

SMAD9r0.0470.0090.0710.100−0.033−0.110
p0.2340.8160.0720.0100.3960.007