Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses

Table 2

Al-induced conformational changes of various proteins.

Proteins	References
Disease-related proteins
Alzheimer’s disease
A𝛽P (1-40)	[64, 131–134]
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVV
A𝛽P (1-42):	[135, 136]
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
A𝛽P (25-35):	[137]
GSNKGAIIGLMV
APP	[138]
Tau or hyperphosphorylated tau (PHF-tau)	[32, 57, 139]
Perkinson’s disease and other diseases with Lewy body
𝛼-synuclein (NACP)	[140, 141]
Type 2 diabetes mellitus
Amylin:	[142]
KCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTY
Familial British dementia
ABri:	[143]
ASNCPAIRHPGNKPAVGTLICSRTVKKNIIGGN
Spinocerebellar ataxia
Ataxin 3	[144]
Dialysis-related arthropathy
𝛽2-microglobulin	[145]