Resting-State Glucose Metabolism Level Is Associated with the Regional Pattern of Amyloid Pathology in Alzheimer's Disease

Table 3

Comparison of the patterns of resting glucose metabolism, glucose hypometabolism, and amyloid deposition in the default and nondefault networks.

Region		Resting metabolism level	Hypometabolism	Amyloid accumulation
Default network	MFG	+	+	+
	MTC	−	−/+	−/+
	LTC	+	+	+
	IP	+	+	+
	PCC	+	+	+
	PFC	+	+	+
	OFC	+	+	+
	HIP	−	−/+	−
Nondefault network	PU	+	−	+
	STG	+	+	+
	TH	+	+	−/+
	VC	+	−	+
	OC	+	−	+
	AMY	−	−	−

−, low effect; +, high effect; −/+, minimal effect.
MFG: middle frontal gyrus, MTC: medial temporal cortex, LTC: lateral temporal cortex, IP: inferior parietal lobe, PCC: posterior cingulate cortex, PFC: prefrontal cortex, OFC: orbitofrontal cortex, HIP: hippocampus, PU: putamen, STG: superior temporal gyrus, TH: thalamus, VC: visual cortex, OC: occipital cortex, AMY: amygdala.