|
Number of low TO genes | Number of genes with high connectivity in region | Significant biological processes/pathways |
|
204 EC-HIP | 115 genes in EC | Regulation of response to stress |
Cell adhesion-ephrin signaling |
Apoptosis and survival-NO synthesis and signaling |
Cell cycle-chromosome condensation in prometaphase |
95 genes in HIP | Mitochondrial translational termination |
Regulation of protein exit from endoplasmic reticulum |
DNA damage-ATM/ATR regulation of G1/S checkpoint |
Immune response |
|
140 EC-MTG | 84 genes in EC | Cell adhesion |
Signal transduction cAMP signaling |
Positive regulation of transcription elongation from RNA polII promoter |
Regulation of transcription involved in G1 phase (mitotic cell cycle) |
Regulation of G2/M transition of mitotic cell cycle |
Apoptosis and survival |
56 genes in MTG | Negative regulation of stress activated MAPK cascade |
Negative regulation of signal transduction |
Activation of astroglial cells proliferation by ACM3 |
Notch signaling pathway |
Regulation of lipid metabolism |
|
242 EC-PCC | 130 genes in EC | Generation of signal involved in cell-cell signaling |
Positive regulation of mitotic cell cycle |
118 genes in PCC | Proteolysis role of parkin |
Immune response IL6 signaling pathway |
p53 signaling pathway |
Activation of ESR1/SP pathway |
|
125 HIP-MTG | 59 genes in HIP | Oxidative phosphorylation |
Neuroligin clustering |
Gephyrin clustering |
Postsynaptic membrane assembly |
Cholesterol and sphingolipids transport |
66 genes in MTG | Transcription |
GTP-XTP metabolism |
ATP/ITP metabolism |
Osmosensory signaling pathway |
Ribonucleotide metabolic process |
|
312 HIP-PCC | 145 genes in PCC | Cell adhesion-ephrin signaling |
Immune response |
Negative adaptation of signaling pathway |
174 genes in HIP | Memory and learning |
Regulation of dopamine metabolic process |
Cognition |
Regulation of calcium ion transport |
NMDA-dependent postsynaptic long-term potentiation |
DNA damage, apoptosis, and survival |
|
158 PCC-MTG | 83 genes in PCC | Positive regulation of protein tyrosine kinase activity |
Neural plate elongation |
Ubiquinone metabolism |
PEDF signaling |
Cytoskeleton remodeling-RalB regulation pathway |
Antiapoptotic TNFs/NF-kB/IAP pathway |
77 genes in MTG | Glucocorticoid receptor signaling |
Positive regulation of transport |
|