|
Number of low TO genes | Number of genes with high connectivity in region | Significant biological processes/pathways |
|
| 204 EC-HIP | 115 genes in EC | Regulation of response to stress |
| Cell adhesion-ephrin signaling |
| Apoptosis and survival-NO synthesis and signaling |
| Cell cycle-chromosome condensation in prometaphase |
| 95 genes in HIP | Mitochondrial translational termination |
| Regulation of protein exit from endoplasmic reticulum |
| DNA damage-ATM/ATR regulation of G1/S checkpoint |
| Immune response |
|
| 140 EC-MTG | 84 genes in EC | Cell adhesion |
| Signal transduction cAMP signaling |
| Positive regulation of transcription elongation from RNA polII promoter |
| Regulation of transcription involved in G1 phase (mitotic cell cycle) |
| Regulation of G2/M transition of mitotic cell cycle |
| Apoptosis and survival |
| 56 genes in MTG | Negative regulation of stress activated MAPK cascade |
| Negative regulation of signal transduction |
| Activation of astroglial cells proliferation by ACM3 |
| Notch signaling pathway |
| Regulation of lipid metabolism |
|
| 242 EC-PCC | 130 genes in EC | Generation of signal involved in cell-cell signaling |
| Positive regulation of mitotic cell cycle |
| 118 genes in PCC | Proteolysis role of parkin |
| Immune response IL6 signaling pathway |
| p53 signaling pathway |
| Activation of ESR1/SP pathway |
|
| 125 HIP-MTG | 59 genes in HIP | Oxidative phosphorylation |
| Neuroligin clustering |
| Gephyrin clustering |
| Postsynaptic membrane assembly |
| Cholesterol and sphingolipids transport |
| 66 genes in MTG | Transcription |
| GTP-XTP metabolism |
| ATP/ITP metabolism |
| Osmosensory signaling pathway |
| Ribonucleotide metabolic process |
|
| 312 HIP-PCC | 145 genes in PCC | Cell adhesion-ephrin signaling |
| Immune response |
| Negative adaptation of signaling pathway |
| 174 genes in HIP | Memory and learning |
| Regulation of dopamine metabolic process |
| Cognition |
| Regulation of calcium ion transport |
| NMDA-dependent postsynaptic long-term potentiation |
| DNA damage, apoptosis, and survival |
|
| 158 PCC-MTG | 83 genes in PCC | Positive regulation of protein tyrosine kinase activity |
| Neural plate elongation |
| Ubiquinone metabolism |
| PEDF signaling |
| Cytoskeleton remodeling-RalB regulation pathway |
| Antiapoptotic TNFs/NF-kB/IAP pathway |
| 77 genes in MTG | Glucocorticoid receptor signaling |
| Positive regulation of transport |
|