Role of CEACAM1, ECM, and Mesenchymal Stem Cells in an Orthotopic Model of Human Breast Cancer
Figure 5
Effect of type and number of stromal cells on the growth and differentiation of MCF7 and MCF7/CEACAM1 xenografts. Gross pictures of human xenografts (left panels) and corresponding H and E stained sections of xenografts (right panels) with hTert/MSC or immortalized breast fibroblasts (RMF/EG) and different ratios of epithelial cells: stromal cells. (a) hTert/MSC : MCF/CEACAM1 ratio 1 : 4 in Matrigel, (b) hTert/MSC : MCF7/CEACAM1 ratio 1 : 1 in Matrigel, (c) RMF/EG along with MCF7/CEACAM1 in Matrigel (1 : 1 ratio), and (d) RMF/EG along with MCF7 in Matrigel. Magnification 200x.
