MRP8/ABCC11 Expression Is Regulated by Dexamethasone in Breast Cancer Cells and Is Associated to Progesterone Receptor Status in Breast Tumors

Figure 1

DEX time-course and dose-dependent effects on ABCC11 mRNA expression. MCF7 cells were exposed to 5 μM DEX for 4 to 72 h (a) or to DEX concentrations ranging from 0.001 to 5 μM (b). Fold change of mRNA levels of ABCC11 was determined by QRT-PCR. The QRT-PCR values indicated below are means ± S.D. of at least 4 independent experiments; 𝑦 is a logarithmic scale. *𝑃<.05; student’s 𝑡-test.

(a)

(b)