Assessment of Pathological Response of Breast Carcinoma in Modified Radical Mastectomy Specimens after Neoadjuvant Chemotherapy

Table 6

Factors affecting the tumor response.

Characteristic	Tumor partial response (pPR)	Tumor complete response (pCR)		OR (95% CI)
Age
Up to 59	27 (73%)	10 (27%)	0.552	0.60 (0.11 to 3.26)
60 and above	9 (81.8%)	2 (18.2%)
Family history
Yes	5 (62.5%)	3 (37.5%)	0.371	0.48 (0.09 to 2.42)
No	31 (77.5%)	9 (22.5%)
Specimen size
Up to 5 cm	26 (70.3%)	11 (29.7%)	0.165	0.23 (0.02 to 2.07)
More than 5 cm	10 (90.9%)	1 (9.1%)
FNA grade
Grade 1	14 (66.7%)	7 (33.3%)	0.240	0.45 (0.12 to 1.71)
Grade 2	22 (81.5%)	5 (18.5%)
DCIS
Yes	11 (84.6%)	2 (15.4%)	0.348	2.20 (0.41 to 11.75)
No	25 (71.4%)	10 (28.6%)
Type of cancer
pCR	1 (11.1%)	8 (88.9%)	<0.001^#	—
Invasive ductal carcinoma NOS	35 (92.1%)	3 (7.9%)
Invasive lobular carcinoma	0	1 (100%)
Lymphovascular invasion
Yes	13 (100%)	0	0.015^#	—
No	23 (65.7%)	12 (34.3%)

Statistically significant.