Research Article
Clinicopathological and Prognostic Characteristics of Malaysian Triple Negative Breast Cancer Patients Undergoing TAC Chemotherapy Regimen
Table 2
Univariate and multivariate Cox analyses on clinicopathological variables and survival of TNBC patients.
| Clinicopathological variables | Disease-free survival | Overall survival | Crude HR | Adjusted HR | Wald statistics (df) | value | Crude HR | Adjusted HR | Wald statistics (df) | value |
| Histology subtype | | | | | | | | | Infiltrating ductal carcinoma | 1.00 | 1.00 | | | 1.00 | 1.00 | | | Other (medullary and metaplastic) | 4.32 (1.83, 10.15) | 5.76 (2.35, 14.08) | 14.71 (1) | 0.001 | 6.46 (1.97, 21.24) | 8.30 (2.38-28.96) | 11.01 (1) | 0.001 | Axillary lymph node metastasis | | | | | | | | | Non-metastasis | 1.00 | 1.00 | | | 1.00 | 1.00 | | | Metastasis | 2.78 (1.16, 6.67) | 3.55 (1.44, 8.74) | 7.62 (1) | 0.006 | 5.01 (1.09, 22.90) | 6.12 (1.32, 28.42) | 5.43 (1) | 0.021 |
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Univariate Cox regression; multivariate Cox regression. value < 0.05, statistically significant based on multivariate Cox regression analysis. |