In Vivo Fluorine Imaging Using 1.5 Tesla MRI for Depiction of Experimental Myocarditis in a Rodent Animal Model

Figure 1

Experimental design used in this study. Animals from the doxorubicin group (upper part of the graphics) or from the control group (lower part) received 6 weekly injections before receiving a single (4 mL) injection of PFC-laden nanoparticles prior to MR-imaging. The animals were then euthanized, and their myocardium was investigated by means of histology and immunohistochemistry.