Research Article
In Vivo Detection of Staphylococcus aureus Infections Using Radiolabeled Antibodies Specific for Bacterial Toxins
Figure 2
In vivo evaluation of [89Zr]Zr-DFO-ToxAb and ex vivo biodistribution. (a) The ex vivo biodistribution in organs of interest () was measured at 1, 24, and 48 h after injection of the radiotracer and expressed as the mean of percent injected dose per gram of tissue (%ID/g). (b) Statistical analysis of the ex vivo biodistribution in infected (blue) and inflamed (grey) soft tissues (; ANOVA, ). (c) Whole body coronal maximum intensity projections (MIPs) (). (d) Region of interest quantification is presented as the ratio of Log10-infected to Log10-inflamed over time (). Data are expressed as the deviation, and the threshold for significance was set at , , and .
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