Effect of Formaldehyde and Curcumin on Histomorphological Indices, Gene Expression Associated with Ovarian Follicular Development, and Total Antioxidant to Oxidant Levels in Wistar Rats

Figure 3

Light micrographs of ovarian tissue (H&E staining). (a) Control, (b) sham, (c) FA, and (d) FA + CUR. Normal histological structure (a, b). Along with a rise in edema in the medulla and vascular hyperemia, more atretic follicles were seen (c). There is less interstitial edema and follicular damage (d). Yellow arrow: graafian follicle, green arrow: secondary follicle, black arrow: atretic follicle, red arrow: primary follicle, and blue arrow: blood vessel; ovarian medulla with edema. Magnification: 10X/scale bar: 100 µm. H&E: hematoxylin and eosin, FA: formaldehyde, and CUR: curcumin.

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